Acute Lymphoblastic Leukemia - 1
IMMUNOPHENOTYPING:
Immature
B-cell ALL:
CALLA
(CD10) positive
Accounts
for 80% of pre-B cell ALLs
CALLA
(CD10) negative
Pre-B-cell
ALL:
2nd most common of ALLs
T-cell
ALL:
TdT
positive
Poorest
prognosis in teenage boys
Cytoplasmic
Immunoglobulin (CIg) positive
B-cell
ALL:
Surface
Immunoglobulin (SIg) positive
Rarest
form of ALL with very poor prognosis
Kappa
or lambda light chain restriction