FAB Classification of AML-1
M0:
AML
with minimal differentiation
<3%
blasts are MPO/SBB positive
No
Auer rods seen
>30%
of marrow nucleated cells are myeloblasts
M1:
AML
without maturation accounts for 20% of AML cases
M:E
ratio >1
>90%
of marrow non-erythroid cells are myeloblasts
>3%
blasts are MPO/SBB positive
M2:
AML
with maturation accounts for 30% of AML cases
>30%
of marrow nucleated cells are myeloblasts
<90%
of marrow non-erythroid cells are myeloblasts
>10%
maturation beyond promyelocyte stage
<20%
of marrow non-erythroid cells are monocytes
Majority
of blasts are MPO/SBB positive