CML
Pathophysiology:
A
clonal process in a pluripotential hematopoietic stem cell
resulting in a chronic phase that eventually transforms
to an accelerated phase then a blast phase that
resembles acute leukemias.
Philadelphia
(ph1)
Cytogenetics:
Translocation
between long arm of 22 to 9 t(9;22)
For further study:
Review
your notes from chapter 34 (Unit 26)