Essential Thrombocytosis (ET)-1
Pathophysiology:
Increased
megakaryopoiesis with thrombocytosis >600 x 109/L
or commonly >1000 x 109/L
Seen
more commonly in older age group
Incidence:
Platelet
count >600 x 109/L
Diagnosis:
Hemoglobin
level <13 g/dL
Negative
for Philadelphia chromosome
Non-fibrous
(<1/3) bone marrow
No
splenomegaly
No
leukoerythroblastosis
No
reactive thrombocytosis