Essential Thrombocytosis (ET)-2
Variation in platelets:
Lab findings:
size
shape
granulation
Distribution – shows clustering of platelets
Increased number of segmented neutrophils
Therapy:
Prevention & alleviation of hemorrhage or vaso-occlusive complications
35P or other alkylating agents to suppress megakaryopoiesis
Interferon-a
Hydroxyurea in young patients