Multiple Myeloma - 1
Incidence:
Median
age:
Also
found rarely in:
63
years
<40
year old
Clinical features:
Bone
lesions due to:
Plasma
cells secrete osteoclast-activating factor
Monoclonal
immunoglobulins: “M spike”
Most
common type:
IgG
2nd Most common type:
IgA
Rarest
types:
IgD & IgE
Light
chains secreted in the urine are called:
Bence-Jones
protein