CLSC411

FAB Classification Features

Feature:

% BLAST PB

<1%

RA

RARS

RAEB

RAEB-t

CMML

% BLAST BM

OTHER

<1%

<5%

>5%

<5%

<5%

<5%

5-20%

20-30%

5-20%

<15% RS

Oval macrocyte

Cytopenia

>15% RS

Dimorph population RBCs

Oval macrocyte

Cytopenia

Cell dysfunction evident

Oval macrocyte

Cytopenia

Absolute monocytosis

Oval macrocyte

Absolute monocytosis

Oval macrocytes

Absolute monocytosis = >1.0 x 109/L

RS = ringed sideroblast

AML will have >30% blasts in bone marrow

PB = peripheral blood

BM = bone marrow