CHEMOTHERAPY AGENTS - 2
Mode
of action:
Anti-tumor antibodies:
Compounds
derived from living microorganisms that inhibit RNA and/or DNA
synthesis
Examples:
Daunorubicin
and doxorubicin
Anti-metabolite agents:
Mode
of action:
Compounds
that interfere with normal functioning of essential
metabolities
Examples:
Methotrexate
– folate antagonist
6-mercaptopurine
– purine analogue
6-thioguanine
– purine analogue