Miscellaneous Disorders
Decreased
number of B-cells with sIg
Primary
Immunodeficiency (Bruton’s agammaglobulinemia):
DiGeorge syndrome:
Decreased
number of T-cells with CD3
AIDS:
Decreased
number of T-cells with CD4
Increased number of T-cells with CD8 (suppressor type)
DNA ploidy:
Aneuploidy
seen in high-grade lymphomas
Diploidy
(normal) seen in low-grade lymphomas
Multiple
myeloma with aneuploidy has short survival
Childhood ALL with aneuploidy has good prognosis with low incidence of relapse