Instrument Calibration
Frequency of calibration:
At initial setup
Minimum of every 6 months
Inability to distinguish between debris and cells of same size:
WBC/RBC cell fragments measured as platelets
Instrument limitations:
Large platelet clumps measured as WBCs
Micromegakaryocytes counted as nRBCs or WBCs
Lyse resistant hemoglobins (S & C) counted as nRBCs or WBCs and decreased Hgb
Specimen limitations:
Study table 40-4 on page 580 of your textbook