Platelet Adhesion
Endothelial
cells damaged
Collagen-rich
basement membrane exposed
Platelets drawn into damaged area by increased turbulence
If
damage is in veins or venules:
Platelets can adhere directly to collage surface
If
damage is in arteries or arterioles:
Von Willebrand factor binds platelet to collagen surface
Platelet
plug lasts only for few hours
Endothelial cells next to damaged area divide and new daughter cells force platelets out.
Fibroblasts
also stimulated to divide.
Steps involved: