Plasma Coagulation System - I
Nomenclature:
Procoagulant:
Glycoproteins that can be activated
Coagulation factors
At least 16 are known
Also called:
Clotting factors
8 are enzymes that circulate in an inactive form called “zymogens”
6 are cofactors that bind and stabilize their respective enzymes
Roman numerals used to designate procoagulants (i.e. I, II, III, IV, V, VII, etc)
When zymogen becomes activate a little letter “a” is used (i.e. Va, VIIa, IXa, etc.)