Cofactors
Mode of
action:
Each
cofactor binds with a specific serine protease
When the serine protease is bound to a cofactor it is more stable and more reactive
Factors that are cofactors:
Tissue
factor (Factor III)
Factor
VIIIa
Factor
Va
HMWK
Protease it binds with:
Factor VIIa
Factor IXa
Factor Xa
Factor XIIa & Kallikrein