Fibrinolysis - II
Plasminogen
Activators (PA):
Free
PA is:
When
bound to fibrin or fibrinogen they:
Factors
considered to be PA:
Bound to Plasminogen Activator Inhibitor-1 (PAI-1)
Convert plasminogen to plasmin
Factors XIIa, kallikrein, factor XIa
Streptokinase
Urokinase
Tissue plasminogen activator (t-PA)
endogenous
exogenous