Liver
Disease - 1
Type of hemorrhage:
Acquired generalized both anatomic
and systemic
Frequency of occurrence:
Most common cause of generalized
hemorrhages
Procoagulant deficiencies:
Vitamin K-dependent
factors:
Mechanisms for hemorrhagic episodes:
II, VII, IX, X,
protein C, & Protein S
Factor VII:
½ life of 5-8 hours so
1st to be decreased
PT is affected
Factor V also decreased
Factors VIII, XIII, and
vWF not affected why?
Produced both in and
out of liver
Are acute phase
proteins
