D.I.C.
in Liver Disease
Disseminated Intravascular
Coagulopathy:
Consumptive Coagulopathy
Alternate names:
Common in liver disease
Cause:
Anti-thrombin proteins
Protein C
Decreased production of:
Release of activated
procoagulants from damaged cells
Protein S
Failure to clear
activated procoagulants by liver
Occurance:
Abnormal tests:
PT, aPTT, TT, FDP,
D-Dimer, factor I
Therapy:
FFP, protein C conc. Or
antithrombin conc.
