Lab
Tests & Liver Disease
Factor
I
>400 mg/dL in early,
mild liver disease
TEST
INTERPRETATION
<200 mg/dL in moderate
- severe liver disease
TT
Prolonged in
dysfibrinogenemia, I deficiency, or elevated FDPs
Reptilase
Prolonged in
dysfibrinogenemia, & I deficiency
PT
Prolonged in mild liver
disease (VII)
Mild prolongation due to
DIC or IX
aPTT
Plt
count
Mild (<150 x 109/L)
Mild suppression – test
variable
Plt
aggreg.
FDPs
Increased levels
D-Dimer
Increased in DIC not in
primary fibrinolysis
Euglobulin
Lysis in < 2 hours in
both 1o & 2o fibrinolysis
