Renal Failure - 1
Type of hemorrhage:
Mild to moderate systemic hemorrhage
Features:
Thrombocytopenia
Altered platelet function
Suppression of platelet aggregation and adhesion due to:
Phenolic compounds and other toxins coating platelets
Decreased RBC and platelet mass leads to bleeding
Acute gastrointestinal lesions leads to GI bleeds
Glomerular damage due to fibrin deposits
Mechanisms: