Congenital
von Willebrand Disease-2
vWF deficiencies:
Mild:
Severe:
Factor VIII deficiency
leads to systemic bleeding
Type 1
Autosomal dominant
Mild systemic bleeding
due to abnormal platelet aggregation
vWF disease types & subtypes:
Most common (80% of vWF
cases)
Decreased levels of vWF
and VIII (variable)
