Hemophilia
B
Factor IX
Factor deficiency:
Christmas disease
14% of congenital
single-factor-deficiencies
A vitamin K dependent factor
Factor
characteristics:
Sex-linked recessive
Inheritance:
Acts as a substrate for factor XI
and VII which activates IX to IXa
Alternate
name:
Incidence:
IXa forms part of the “Tenase
complex” (IXa, VIIIa, Ca++, and PF3) to convert X to Xa
