Venous
vs Arterial Thrombosis
Venous
Feature
Arterial
Incidence
1 in 1000
80% of MI’s
85% of strokes
95% of pulmonary emboli come from deep veins of legs
Mechanisms
Coagulation system imbalances (activation & control) with inadequate fibrinolytic response
Plaque formation that inhibits release of antithrombic agents such as nitric acid
and exposes prothrombic agents such as tissue factor
Plaques fragment blocking vessels and activate platelets
