Diseases & Risk Factors - 2
Elevated fibrinogen and VIII levels
Decreased fibrinolysis
Chronic inflammation:
Thrombotic episodes may be due to either:
Cancer:
Reduced levels of free protein S secondary to increased C4b-binding protein
Increased production of tissue factor
Increased stasis
Promotion of arteriosclerotic plaques
Leukemia:
Acute promyelocytic (M3) associated with D.I.C.