CLSC412 HEMOSTASIS

Lab Analysis – Acquired Risk Factors - 2

von Willebrand factor

Coagulation Factor assays:

I - fibrinogen

VII

Plasma Homocysteine assays:

Elevated levels seen in 5-15% of general population

VIII

Protein C

Triggers arterial thrombosis and is seen in:

42% of stroke patients

30% of coronary artery disease

28% of peripheral vascular disease

Protein S

Antithrombin

Also seen in folate, B6, B12 deficiencies :

Levels influenced by mutations in MTHFR gene, methionine synthase gene, or CBS gene