Clinical Features of APL
1-2% of population test positive for APL
Incidence:
5-15% of individuals with recurrent venous or arterial thrombosis test positive for APL
Alloimmune APL antibodies:
The majority of APL antibodies are this type
Associated with bacterial/viral/parasitic infections
Disappear in 6 weeks
Autoimmune APL antibodies:
50% of SLE patients have APL antibodies
Rheumatoid Arthritis and Sjögren syndrome
Types of APL antibodies: