Protein
C & Protein S
Mechanism of antithrombic action
Click here to review mode of action
Two forms of
Protein S:
Free: only form able to interact with protein C
Bound: protein S is bound to C4bBp and is unavailable to react with protein C
Protein C
& Protein S deficiencies:
2 – 5 fold increased risk of
recurrent deep vein thrombosis and pulmonary embolism
Protein S deficiencies also
implicated in:
Transient ischemic
attacks
CVA - strokes
