Characteristics
of Protein C & Protein S
Group they belong to:
Prothrombin group
Vitamin K dependent group
Factors II, VII, IX, and X also in
this group
½ life of
Protein C & Protein S:
6 hours
Levels of Protein C and Protein S
drop faster than VII with start of coumadin therapy so:
Heparin is administered
for at least 5 days prior to switching just to coumadin
After coumadin therapy stopped -
Two weeks before effects
disappear
