Coagulation
Control Proteins in D.I.C.
Protein
C
Control
proteins:
Protein
S
They are consumed which allows coagulation to continue in areas away from site of injury
and other coagulation factors are consumed in process
Patient presents with hemorrhagic features due to consumption of coagulation proteins
Antithrombin
Outcome in D.I.C.:
Control proteins during D.I.C.:
Symptoms of D.I.C.:
Combination
of systemic and anatomic bleeding
Skin, bone, and bone marrow necrosis may be seen due to thrombi in microvascular
system
