Therapy for HIT
Immediately stop heparin therapy
The following therapy is contraindicated:
Low-molecular weight heparin
Donaparoid:
Coumadin may induce skin necrosis syndrome
Need to monitor with ant-Xa assay
May use the following heparin analogs:
Lepirudin:
Argatroban:
Need to monitor with aPTT or ecarin prothrombin assay (venom from snake Echis carinatus
Direct thrombin inhibitor
Monitor using aPTT
Recombinant thrombin inhibitor
Treatment: