Acute ITP - 1
Incidence:
2 – 5 year old children mainly (4/100,000)
Abupt onset of bruising, petechiae, and/or mucosal bleeding
Within 1 – 3 weeks following infections:
Features:
Onset:
Upper respiratory tract
Gastrointestinal tract viral infection
Rubella, rubeola
Chicken pox
Mechanism:
Antibodies to virus/bacteria form antibody-antigen complexes that bind to surface of platelets