Immune
Drug-induced - 3
Mechanisms
involved: continued
Type 2:
antibody with drug by FAb
portion and the Fc portion binds with Fc receptor on platelet causing activation of
platelet
platelet
antibody
drug
Heparin-induced
Less severe
Thrombosis may occur
7-14 days initial
exposure
1-3 days subsequent
exp.
Daily plt counts when
on heparin