Meloproliferative
Disorders
Essential Thrombocytosis (ET):
Platelet counts in excess of 1000.0
x 109/L
Acquired disfunction of
pluripotential stem cell
Middle-aged to elderly male &
females equally
Therapy is myelosuppressive agents,
plateletphersis, interferon-a (60% remission), and anagrelide (suppresses megakaryocyte maturation
in 93% of cases)