Glanzmann's Thrombasthenia -2
Laboratory
features:
Normal
platelet morphology
Normal
platelet count
Prolonged
bleeding time
Abnormal
clot retraction studies
Aggregation
studies:
Abnormal aggregation to all aggregating agents except ristocetin
which is normal
Platelet
Factor 3 (PF3) studies abnormal
Clinical features:
Severe
and disabling
Treatment:
Platelet
transfusions
Alloantibodies may be formed
Apheresis unit one of choice