Function of TxA2
Required
for platelets to secrete granular contents
Platelet
secretion :
Required
for platelet aggregation in response to:
Platelet aggregation :
ADP
epinephrine
Low concentrations of collagen
Thrombin and TxA2 :
Thrombin stimulates the release of thromboxane A2 from platelets
Aspirin-like defects :
Congenital and acquired abnormalities of components of the thromboxane
pathway