Disorders & Platelet Function - 1
Polycythemia vera
Chronic Myeloproliferative Disorders such as:
Chronic myelogenous leukemia
Essential thrombocytosis
Myelofibrosis
Multiple Myeloma &                                                           Waldenström macgroglobulinemia:
Myeloid metaplasia
IgA type Multiple myeloma
IgM of Waldenström’s
1/3 of patients with the following will have platelet dysfunction:
Platelets are coated with Ig’s (paraproteins) and they interfere with fibrin polymerization