Platelet
Poor Plasma (PPP)
Definition:
Plasma that contains <10 x 109/L
of platelets after centrifugation
Preparation:
Specimen is centrifuged for 15
minutes at 1500g
All clot-based testing
Tests using
PPP:
Factors that
platelets may release and their affects on clot-based
testing:
phosphatidylserine
I, V, VIII, vWF
PF4
Neutralizes lupus
anticoagulant
May shorten assay time
Antagonist to heparin