PT
- 4
Monitoring function:
Clinical application:
Effects of oral
anticoagulant therapy using warfarin-based dervivatives of 4-hydroxycoumarin
Review vitamin-K
antagonist mechanism from unit 43
Diagnostic function:
Prolonged PT seen in
following disorders:
D.I.C.
liver
renal
Vitamin K deficiency
Effect
VII
malnutrition
Broad-spectrum
antibiotics
newborns
Single factor
deficiency:
X,
VII, V, II, I (<100 mg/dL)