Prolongation
of aPTT
D.I.C.
Vitamin K deficiencies because:
Factors II, IX, and X
are vitamin K dependent
Single-factor deficiencies in
intrinsic and common pathways:
Disorders causing prolonged aPTT:
Circulating anticoagulants or
inhibitors:
Factors XII, IX, IX,
VIII, X, II, V, I
Lupus anticoagulant
Anti-Factor VIII