CLSC412 HEMOSTASIS

PT Single-Factor Assay - 1

If aPTT and PT are abnormal and TT is normal and normal plasma corrects aPTT and PT then a single-factor deficiency in the common pathway may be to blame

Principle :

Factor X

Factor V

Factor II

Most common factor deficiencies :

If only the PT is abnormal and aPTT and TT are normal and normal plasma corrects the PT then a single-factor deficiency in the extrinsic pathway may be to blame

Factor VII – if only PT is abnormal

Procedure :

Same as that for aPTT but PT test performed and appropriate factor deficient plasmas used