Platelet Function Instrumentation
PFA 100 by Dade Behring Inc.:
Membranes coated with collagen/epinephrine or collagen/ADP and possessing a small orifice
Sample (anticoagulated whole blood) is aspirated through orifice using set flow conditions
Time for platelets to adhere and aggregate to stop flow is measured
CSA – Clot Signature Analyzer:
Measures collagen-induced clot formation time
Uses non-anticoagulated whole blood and measures the time it takes for platelets to stop flow of sample through small tubing