Second Generation Azatilbenes

Maurice Hardy (Chemistry and Biochemistry)

Synthesis and testing of second generation azatilbenes

Based on previous research, azastilbenes have been reported as effective chemical sensors for organophosphates and organothiophosphates; they are related classes and the active components of agricultural pesticides, environmental pollutants and chemical warfare agents. This project builds on previous work and involves the synthesis of a variety of these azastilbenes and the testing of their respective properties. Azastilbene sensors are prepared using high-yield organic synthetic methodology developed in Professor Murray's lab. The next step involves testing the sensors through a measure, by UV-Vis spectroscopy and fluorometry, of an optical change upon the addition of analyte to a solution containing azastilbene sensor.

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